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1

Cellular Inhibition of Protein Tyrosine Phosphatase 1B by Uncharged Thioxothiazolidinone Derivatives

Matthew Stuible, Liang Zhao, Isabelle Aubry, Dirk Schmidt-Arras, Frank-D. Böhmer, Chao-Jun Li, Michel L. Tremblay

Journal:

Year:

2007

Language:

english

File:

PDF, 308 KB

english, 2007

2

Adaptation of a 2D in-gel kinase assay to trace phosphotransferase activities in the human pathogen Leishmania donovani

Dirk Schmidt-Arras, Olivier Leclercq, Pier Federico Gherardini, Manuela Helmer-Citterich, Wolfgang Faigle, Damarys Loew, Gerald F. Späth

Journal:

Journal of Proteomics

Year:

2011

Language:

english

File:

PDF, 711 KB

english, 2011

3

Functional significance of novel neurotrophin-1/B cell-stimulating factor-3 (cardiotrophin-like cytokine) for human myeloma cell growth and survival

Renate Burger, Frank Bakker, Andreas Guenther, Wolfgang Baum, Dirk Schmidt-Arras, Teru Hideshima, Yu-Tzu Tai, Reshma Shringarpure, Laurence Catley, Giorgio Senaldi, Martin Gramatzki, Kenneth C. Anders

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 542 KB

english, 2003

4

The pro- and anti-inflammatory properties of the cytokine interleukin-6

Jürgen Scheller, Athena Chalaris, Dirk Schmidt-Arras, Stefan Rose-John

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 788 KB

english, 2011

5

Mislocalized Activation of Oncogenic RTKs Switches Downstream Signaling Outcomes

Chunaram Choudhary, Jesper V. Olsen, Christian Brandts, Jürgen Cox, Pavankumar N.G. Reddy, Frank D. Böhmer, Volker Gerke, Dirk-E. Schmidt-Arras, Wolfgang E. Berdel, Carsten Müller-Tidow, Matthias Mann

Journal:

Year:

2009

Language:

english

File:

PDF, 1.70 MB

english, 2009

6

Interleukin-6 Trans-Signaling and Colonic Cancer Associated with Inflammatory Bowel Disease

Chalaris, Athena, Schmidt-Arras, Dirk, Yamamoto, Kosuke, Rose-John, Stefan

Journal:

Digestive Diseases

Year:

2012

Language:

english

File:

PDF, 520 KB

english, 2012

7

The Crystal Structure of the MAP Kinase LmaMPK10 from Leishmania Major Reveals Parasite-Specific Features and Regulatory Mechanisms

Sofía Horjales, Dirk Schmidt-Arras, Ramiro Rodriguez Limardo, Olivier Leclercq, Gonzalo Obal, Eric Prina, Adrian G. Turjanski, Gerald F. Späth, Alejandro Buschiazzo

Journal:

Year:

2012

Language:

english

File:

PDF, 3.45 MB

english, 2012

8

Short-term TNFα shedding is independent of cytoplasmic phosphorylation or furin cleavage of ADAM17

Schwarz, Jeanette, Broder, Claudia, Helmstetter, Ansgard, Schmidt, Stefanie, Yan, Isabell, Müller, Miryam, Schmidt-Arras, Dirk, Becker-Pauly, Christoph, Koch-Nolte, Friedrich, Mittrücker, Hans-Willi,

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2013

Language:

english

File:

PDF, 1.01 MB

english, 2013

9

Design and Biological Evaluation of Linear and Cyclic Phosphopeptide Ligands of the N-Terminal SH2 Domain of Protein Tyrosine Phosphatase SHP-1

Imhof, Diana, Wieligmann, Karin, Hampel, Kornelia, Nothmann, Doreen, Zoda, Mohammad S., Schmidt-Arras, Dirk, Zacharias, Martin, Böhmer, Frank D., Reissmann, Siegmund

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 464 KB

english, 2005

10

Oncogenic deletion mutants of gp130 signal from intracellular compartments

Schmidt-Arras, D., Muller, M., Stevanovic, M., Horn, S., Schutt, A., Bergmann, J., Wilkens, R., Lickert, A., Rose-John, S.

Journal:

Journal of Cell Science

Year:

2014

Language:

english

File:

PDF, 3.99 MB

english, 2014

11

Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases

Schmidt-Arras, D.-E., Bohmer, A., Markova, B., Choudhary, C., Serve, H., Bohmer, F.-D.

Journal:

Molecular and Cellular Biology

Year:

2005

Language:

english

File:

PDF, 1.06 MB

english, 2005

12

Polo-like Kinase 2, a Novel ADAM17 Signaling Component, Regulates Tumor Necrosis Factor Ectodomain Shedding

Schwarz, J., Schmidt, S., Will, O., Koudelka, T., Kohler, K., Boss, M., Rabe, B., Tholey, A., Scheller, J., Schmidt-Arras, D., Schwake, M., Rose-John, S., Chalaris, A.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.16 MB

english, 2014

13

Hepatocytes Contribute to Immune Regulation in the Liver by Activation of the Notch Signaling Pathway in T Cells

Burghardt, S., Erhardt, A., Claass, B., Huber, S., Adler, G., Jacobs, T., Chalaris, A., Schmidt-Arras, D., Rose-John, S., Karimi, K., Tiegs, G.

Journal:

The Journal of Immunology

Year:

2013

Language:

english

File:

PDF, 1.81 MB

english, 2013

14

Cyclosporin A Treatment of Leishmania donovani Reveals Stage-Specific Functions of Cyclophilins in Parasite Proliferation and Viability

Yau, Wai-Lok, Blisnick, Thierry, Taly, Jean-François, Helmer-Citterich, Manuela, Schiene-Fischer, Cordelia, Leclercq, Olivier, Li, Jing, Schmidt-Arras, Dirk, Morales, Miguel A., Notredame, Cedric, Rom

Journal:

PLoS Neglected Tropical Diseases

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

15

Transgenic Analysis of the Leishmania MAP Kinase MPK10 Reveals an Auto-inhibitory Mechanism Crucial for Stage-Regulated Activity and Parasite Viability

Cayla, Mathieu, Rachidi, Najma, Leclercq, Olivier, Schmidt-Arras, Dirk, Rosenqvist, Heidi, Wiese, Martin, Späth, Gerald F., Jaffe, Charles L.

Journal:

Year:

2014

Language:

english

File:

PDF, 4.42 MB

english, 2014

16

Flt3 Receptor Tyrosine Kinase as a Drug Target in Leukemia

Schmidt-Arras, Dirk, Schwable, Joachim, Bohmer, Frank-, Serve, Hubert

Journal:

Current Pharmaceutical Design

Year:

2004

Language:

english

File:

PDF, 248 KB

english, 2004

17

IL-6 pathway in the liver: from physiopathology to therapy

Schmidt-Arras, Dirk, Rose-John, Stefan

Journal:

Journal of Hepatology

Year:

2016

Language:

english

File:

PDF, 2.06 MB

english, 2016

18

Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains

Schmidt, Frederike, Müller, Miryam, Prox, Johannes, Arnold, Philipp, Schönherr, Caroline, Tredup, Claudia, Minder, Petra, Ebsen, Henriette, Janssen, Ottmar, Annaert, Wim, Pietrzik, Claus, Schmidt-Arra

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.46 MB

english, 2016

19

Tetraspanin 8 is an interactor of the metalloprotease meprin β within tetraspanin-enriched microdomains

Schmidt, Frederike, Müller, Miryam, Prox, Johannes, Arnold, Philipp, Schönherr, Caroline, Tredup, Claudia, Minder, Petra, Ebsen, Henriette, Janssen, Ottmar, Annaert, Wim, Pietrzik, Claus, Schmidt-Arra

Journal:

Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 1.28 MB

english, 2016

20

P0302 : Constitutive gp130 activation accelerates transformation of proliferating human hepatocytes via increased levels of oxidative stress

Gil-Ibanez, I., Heim, D., Herden, J., Parplys, A.C., Borgmann, K., Schmidt-Arras, D., Lohse, A.W., Rose-John, S., Wege, H.

Journal:

Journal of Hepatology

Year:

2015

Language:

english

File:

PDF, 212 KB

english, 2015

21

The Murine Choline-Deficient, Ethionine-Supplemented (CDE) Diet Model of Chronic Liver Injury

Gogoi-Tiwari, Jully, Köhn-Gaone, Julia, Giles, Corey, Schmidt-Arras, Dirk, Gratte, Francis D., Elsegood, Caryn L., McCaughan, Geoffrey W., Ramm, Grant A., Olynyk, John K., Tirnitz-Parker, Janina E.E.

Journal:

Journal of Visualized Experiments

Year:

2017

Language:

english

File:

PDF, 1.42 MB

english, 2017

22

Early heme oxygenase 1 induction delays tumour initiation and enhances DNA damage repair in liver macrophages of Mdr2−/− mice

Barikbin, Roja, Berkhout, Laura, Bolik, Julia, Schmidt-Arras, Dirk, Ernst, Thomas, Ittrich, Harald, Adam, Gerhard, Parplys, Ann, Casar, Christian, Krech, Till, Karimi, Khalil, Sass, Gabriele, Tiegs, G

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.25 MB

english, 2018

23

Degradome of soluble ADAM10 and ADAM17 metalloproteases

Scharfenberg, Franka, Helbig, Andreas, Sammel, Martin, Benzel, Julia, Schlomann, Uwe, Peters, Florian, Wichert, Rielana, Bettendorff, Maximilian, Schmidt-Arras, Dirk, Rose-John, Stefan, Moali, Catheri

Journal:

Cellular and Molecular Life Sciences

Year:

2019

Language:

english

File:

PDF, 2.23 MB

english, 2019

24

Gut microbiota shape ‘inflamm-ageing’ cytokines and account for age-dependent decline in DNA damage repair

Guedj, Avital, Volman, Yael, Geiger-Maor, Anat, Bolik, Julia, Schumacher, Neele, Künzel, Sven, Baines, John F, Nevo, Yuval, Elgavish, Sharona, Galun, Eithan, Amsalem, Hagai, Schmidt-Arras, Dirk, Rachm

Journal:

Year:

2019

Language:

english

File:

PDF, 8.40 MB

english, 2019

25

Gut microbiota shape ‘inflamm-ageing’ cytokines and account for age-dependent decline in DNA damage repair

Guedj, Avital, Volman, Yael, Geiger-Maor, Anat, Bolik, Julia, Schumacher, Neele, Künzel, Sven, Baines, John F, Nevo, Yuval, Elgavish, Sharona, Galun, Eithan, Amsalem, Hagai, Schmidt-Arras, Dirk, Rachm

Journal:

Year:

2019

File:

PDF, 8.40 MB

2019

26

Mislocalisation of Activated Receptor Tyrosine Kinases â Challenges for Cancer Therapy

Schmidt-Arras, Dirk, BÃ¶hmer, Frank-D.

Journal:

Trends in Molecular Medicine

Year:

2020

File:

PDF, 1.76 MB

2020

27

ADAM-Mediated Signalling Pathways in Gastrointestinal Cancer Formation

Schumacher, Neele, Rose-John, Stefan, Schmidt-Arras, Dirk

Journal:

International Journal of Molecular Sciences

Year:

2020

File:

PDF, 1.57 MB

2020

28

Novel Approaches to Target Mutant FLT3 Leukaemia

MÃ¼ller, JÃ¶rg P., Schmidt-Arras, Dirk

Journal:

Year:

2020

File:

PDF, 898 KB

2020